NOMATEN HYBRID-SEMINAR April 9: Radiolabeling of biomolecules for applications in PET imaging

Date
2026-04-09, 13:00

NOMATEN HYBRID-SEMINAR

online: https://meet.goto.com/NCBJmeetings/nomaten-seminar
In-person: NOMATEN seminar room (102)

Thursday, April 9th  2026 13:00 PM (CET)

Radiolabeling of biomolecules for applications in PET imaging

Mylène Richard, Dr.
CEA / Institut des sciences du vivant Frédéric Joliot / SHFJ (Service Hospitalier Frédéric Joliot) / BIOMAPS, France.

 

Abstract:

Radiolabeled biomolecules are increasingly employed for diagnostic and treatment. Amongst available imaging radioisotopes, fluorine-18 presents many advantages (ease of production, optimal physical properties and short half-life) and is the most commonly used PET isotope. However, the fragility and complexity of biomolecules are not always compatible with the harsh conditions usually required for radiofluorination. To sidestep these problems, several methods (isotopic exchange, 2-step prosthetic strategies) have been developed and implemented over the years. This talk will present an overview of our work in this field.
 

Bio:

Mylène Richard completed her PhD in organic chemistry in 2015 at the university of Lorraine (supervisor: Dr Nadia Pellegrini-Moïse). During her PhD, she worked on sugar-based peptidomimetics and exo-glycals reactivity. She then joined the group of Pr Ben Davis at the University of Oxford for a 2-years post-doctoral training in chemical biology. She worked on antibody-drug conjugates and protein modification with thiosugars. In 2017, she was recruited at the French Alternative Energies and Atomic Energy Commission (CEA) in the Service Hospitalier Frédéric Joliot (SHFJ). Her research is now focused on the radiolabeling of (bio)molecules for PET imaging and therapeutic applications.

 

 

Tags



This project has received funding from the European Union Horizon 2020 research and innovation
programme under grant agreement No 857470 and from European Regional Development Fund
via Foundation for Polish Science International Research Agenda PLUS programme grant
No MAB PLUS/2018/8.
Poland
The project is co-financed from the state budget within the framework of the undertaking of the Minister of Science and Higher Education "Support for the activities of Centers of Excellence established under Horizon 2020".

Grant: 5 143 237,70 EUR
Total value: 29 971 365,00 EUR
Date of signing the funding agreement: December 2023

The purpose of the undertaking is to support entities of the higher education and science system that have received funding from the European Union budget in the competition H2020-WIDESPREAD-2018-2020/WIDESPREAD-01-2018-2019: Teaming Phase 2. in the preparation, implementation and updating of activities, maintenance of material resources necessary for carrying out activities, acquisition and modernization of scientific and research apparatus, maintenance and development of personnel potential necessary for the implementation of activities, and dissemination of the results of scientific activities.